Comparing Normalization Methods Based on Splice Array Experiments
Place: IMA, University of Minnesota, Minneapolis, NM..
Date: Sept 29 - Oct 3, 2003
Abstract:
There are many sources of systematic variation in
microarray experiments that affect measured gene
expression levels. Normalization is the term used to
describe the process of removing such variations. In this talk,
I will describe a set of experiments based on splice-specific
microarrays. These arrays provide a basis to investigate the effect of
mutations and other factors on splicing events in the creation of mature
mRNA. In particular, the design of these arrays provides a platform for
comparing the performance of different normalization methods.
Slides: Download [pdf file]