Schedule:
Sep 14 (Lecture 1): Dr. Ru-Fang Yeh:
Overview of
statistical issues in bioinformatics. Introduction to
microarray analysis;
slides
Sep 21 (Lecture
2): Dr. Ru-Fang Yeh:
Clustering; Tiling array analysis: ChIP-chip for histone modifications in tumors.
slides
Sep
28 (Lecture 3): Dr.
Yuan-Yuan Xiao
Exploration and analysis of Affymetrix SNP arrays
slides
Oct 5 (Lecture 4): Dr.
Jane Fridlyand
Copy number
arrays and example of meta-analysis of
genomic data:
Demonstration of the methodology on the breast cancer data;
slides
Oct 12 (Lecture 5): Dr. Jane Fridlyand
Data Integration (continiued) and Classification
in genomics: Application to tumor data;
slides
Oct 19 (Lecture
6): Dr. Mark
Segal
Validation
in genomics: CpG island methylation revisited;
slides
Oct 26 (Lecture 7): Drs. Mark Segal & Yuan-Yuan Xiao
E-values for protein database searches
based on tandem mass spectrometry scoring;
slides
Challenges in mass-spectrometry data analysis;
slides
Nov 2 (Lecture 8): Dr. Haiyan Huang,
UC Berkeley
A
statistical framework to infer functional gene associations from
multiple
biologically
interrelated microarray experiments: application to yeast and
human data;
Nov 9 (Lecture 9): Dr.
Imola Fodor, LLNL
Phenotypic
characterization of
Yersinia pestis;
Nov
16 (Lecture 10): Dr.
Katie Pollard, UC Davis
Detecting
lineage-specific evolution of DNA.
Grades:
100% - classroom participation
Recommended
readings:
